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Tsunade (綱手) is a descendant of the Senju and Uzumaki Clan and is one of Konohagakure's Sannin. She is famed as the world's strongest kunoichi and its greatest medical-nin. The repeated loss of her loved ones caused Tsunade to later abandon the life of a shinobi for many years. She is eventually persuaded to return to Konoha and take on the mantle of Fifth Hokage (五代目火影, Godaime Hokage, literally meaning: Fifth Fire Shadow), where her skills prove invaluable to the village.As a descendant of both the Senju and Uzumaki Clans, Tsunade inherited their life-force and physical energy, allowing her to still fight at peak performance despite her naturally frail form and battle the likes of Madara Uchiha for over half a day without exhaustion. She can even endure several mortal stabs to the chest[35] and retain consciousness after being bisected[36] long enough to heal others before being healed herself. Her reserves of chakra are immense, enough to heal several thousand shinobi during the final battle with Obito Uchiha. In addition, Tsunade has excellent control over her chakra, able to perform her various feats to the maximum efficiency with absolute minimum required chakra and build-up time. Her timing and precision for focusing her chakra is so advanced, by releasing it in parts of her body at the key point of contact, she can further her strength to decimate a target, even break through an "absolute defence" in Susanoo, with a single blow, which led to Madara praising her as having greater raw power than the Fourth Raikage.The Sannin (伝説の三忍, Densetsu no Sannin, literally meaning: Legendary Three Ninja) were three renowned ninja from Konohagakure, hailed as the greatest of their time.Chōmei (重明), more commonly known as the Seven-Tails (七尾, Nanabi, Shichibi), is one of the nine tailed beasts. It was last sealed within Nora Uzumaki from Takigakure.Chōmei (重明), more commonly known as the Seven-Tails (七尾, Nanabi, Shichibi), is one of the nine tailed beasts. It was last